Synthesis of some N-benzylphosphoryl chitosan derivatives and their fungicidal and insecticidal activity

Document Type : Original Article

Authors

1 Department of Pesticide Chemistry, Faculty of Agriculture,El-Shatby, Alexandria University, Egypt

2 Department of Pest Control and Environmental Protection; Faculty of Agriculture, Damanhour, Alexandria University, Egypt

10.21608/jpces.2005.459538

Abstract

A series of some water-soluble N-benzy)phosphoryl chitosan (NBPC) derivatives were synthesized by reaction of chitosan with aldehydes and phosphorus acid. Chemical identification was confirmed by IH- and 31P-NMR spectroscopy. Their biological activities were tested against economic fungus of the grey mould, Botrytis cinerea, and insect of the cotton leafeworm, Spodoptera littoralis. In a radial growth fungicidal bioassay, all of the synthetic compounds were about 6 times more potent than natural chitosan. Substitution with 0-nitro group on the phenyl ring showed the highest activity (EC50 = 0.04%), whereas substitution with p-cyano was the lowest one (EC50 = 0.19%). In feeding bioassay, the insecticidal activity was screened against third-instar larvae Of the cotton leafworm, S littoralis, at 0.5 % (w/w) in the artificial diet and the most active compound was also N(0-nitrobenzylphosphoryl) chitosan.

Keywords

Journal of Pest Control and Environmental Sciences
Volume 13, Issue 2
December 2005
Pages 43-56

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